Tim Lezon

Tim Lezon

I am an Assistant Professor of Computational and Systems Biology and Clinical and Translational Science at the University of Pittsburgh. My research interests include understanding the origins of non-genetic cellular heterogeneity and predicting synergistic effects of combination therapeutics for cancer and neurodegenerative disease. I lead the systems biology and modeling group at the University of Pittsburgh Drug Discovery Institute. My previous work focused on the physics of protein folding and protein structural dynamics.


I am the Executive Director of the Computational Biomedicine and Biotechnology (CoBB) master's program at Pitt, and I teach Introduction to Computational Structural Biology and Foundations in Computational Biology. Some of my lecture notes are here.

CTSI Biomedical Modeling Core

I also direct the Biomedical Modeling Core for the Clinical and Translational Science Institute (CTSI) at the University of Pittsburgh. The goal of the core is to make computational approaches for prediction accessible and useful to a wide variety of clinical and translational investigators. Please contact me for more details, or if you are looking for help establishing a trans-disciplinary collaboration.